El próximo viernes 22 de abril, a las 11:30 h, contaremos con la participación del Dr. Leonardo Beccari (INSTITUT NEUROMYOGÈNE, Université Claude Bernard Lyon 1) que impartirá la conferencia titulada Role of enhancer activity and chromatin architecture on the regulation and evolution of developmental gene expression: The HoxD cluster paradigm. Esta conferencia ha sido organizada por el profesor Miguel Ángel Medina del Dpto. de Biología Molecular y Bioquímica.
Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster. Amândio AR et al. Genes Dev. 2021. 35:1490-1509.
Dbx2 regulation in limbs suggests interTAD sharing of enhancers. Beccari L, et al. Dev Dyn. 2021. 250:1280-1299.
Chromatin topology and the timing of enhancer function at the HoxD locus. Rodríguez-Carballo E, et al. PNAS. 2020. 117:31231-31241.
An evolutionarily-conserved Wnt3/β-catenin/Sp5 feedback loop restricts head organizer activity in Hydra. Vogg MC, et al. Nat Commun. 2019. 10:312.
Similarities and differences in the regulation of HoxD genes during chick and mouse limb development. Yakushiji-Kaminatsui N, et al. PLoS Biol. 2018. 16:e3000004.
