Conferencia: Alzheimer y nanomedicina.

El próximo viernes 19 de marzo, a las 12 h, tendrá lugar la 4ª conferencia de nuestro ciclo 2020-21. En esta ocasión, la Dra. Joana A. Loureiro (LEPABE, Oporto, Portugal) nos impartirá la conferencia Liposomebased nanocarriers to transport drugs for the Alzheimer´s disease treatment. La Dr. Loureiro ha sido invitada por la investigadora Inés Moreno (Dpto. Biología Celular, Genética y Fisiología, UMA). Debido a la situación de emergencia sanitaria por COVID-19, la conferencia tendrá lugar online a través de la plataforma Google Meet. Podréis acceder mediante el siguiente enlace: meet.google.com/ccc-ntvn-sei

Breve reseña de la trayectoria investigadora: Dr. Joana A. Loureiro is a researcher at the Laboratory for Process Engineering, Environment, Biotechnology and Energy (LEPABE) since 2010 and Invited Assistant Professor at Faculty of Engineering, University of Porto (FEUP) since 2018. Joana did her bachelors and masters in chemical engineering followed by a bachelors and masters in pharmaceutical sciences. She received her PhD degree in chemical and biological engineering from FEUP in 2013. Since 2010, Joana has been working in the field of drug delivery nanosystems for brain diseases treatment. She has expertise in protein misfolding and pathogenic biomarkers associated with Alzheimer’s disease. Her main research areas of interest comprises: i) nanotechnology and interfacial phenomena; ii) effects of fluorinated systems and peptides on the aggregation of amyloid-beta peptide; iii) conformational studies of proteins and peptides self-organized systems and polymer surfaces; and iv) design and production of inorganic and polymeric nano-systems for pharmaceutical application.

Recent publications:

In vivo Bio-Distribution and Toxicity Evaluation of Polymeric and Lipid-Based Nanoparticles: A Potential Approach for Chronic Diseases Treatment. Fonseca-Gomes J, Loureiro JA, Tanqueiro SR, Mouro FM, Ruivo P, Carvalho T, Sebastião AM, Diógenes MJ, Pereira MC. Int J Nanomedicine. 2020 Nov 5;15:8609-8621.

PLGA Based Drug Carrier and Pharmaceutical Applications: The Most Recent Advances. Loureiro JA, Pereira MC. Pharmaceutics. 2020 Sep 22;12(9):903.

 RVG29-Functionalized Lipid Nanoparticles for Quercetin Brain Delivery and Alzheimer’s Disease.Pinheiro RGR, Granja A, Loureiro JA, Pereira MC, Pinheiro M, Neves AR, Reis S. Pharm Res. 2020 Jul 13;37(7):139.

Double Optimization of Rivastigmine-Loaded Nanostructured Lipid Carriers (NLC) for Nose-to-Brain Delivery Using the Quality by Design (QbD) Approach: Formulation Variables and Instrumental Parameters. Cunha S, Costa CP, Loureiro JA, Alves J, Peixoto AF, Forbes B, Sousa Lobo JM, Silva AC. Pharmaceutics. 2020 Jun 28;12(7):599.

Molecular interactions between Vitamin B12 and membrane models: A biophysical study for new insights into the bioavailability of Vitamin.Ramalho MJ, Andrade S, Coelho MAN, Loureiro JA, Pereira MC. Colloids Surf B Biointerfaces. 2020 Oct;194:111187.

Fluorinated Molecules and Nanotechnology: Future ‘Avengers’ against the Alzheimer’s Disease? Dabur M, Loureiro JA, Pereira MC. Int J Mol Sci. 2020 Apr 23;21(8):2989.

Immuno-nanocarriers for brain delivery: limitations from in vitro to preclinical and clinical studies. Loureiro JA, Ramalho MJ, Carmo Pereira MD. Nanomedicine (Lond). 2020 Mar;15(6):543-545.

La Dra. Loureiro nos ha proporcionado estos enlaces en los que encontraréis información complementaria a su charla:

Liposomas: conceptos básicos (parte I)
Liposomas: conceptos básicos (parte II)

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